Assessment of Antioxidant, Antibacterial, and Preliminary Cytotoxic Properties of Brownlowia Tersa

Abstract

Antioxidant, antibacterial, and brine shrimp lethality bioassay of Brownlowia tersa leaf and bark extracts were performed. The half maximal inhibitory concentration (IC50) values in DPPH free radical scavenging assay for the bark and leaf extracts of petroleum ether, chloroform, and methanol were 102.09 ± 0.53, 236.28 ± 0.85, 27.90 ± 0.56, and 183.74 ± 0.75, 45.78 ± 0.27, and 35.12 ± 0.55 µg mL−1, respectively. Total phenolic content was the higher in methanolic bark and leaf extracts than in other solvents. Total flavonoid content was the highest in the methanolic leaf extracts and the lowest in chloroform bark extract. Petroleum ether and methanolic extracts of bark and leaf demonstrated antibacterial activity against Escherichia coli ATCC 28739 and Pseudomonas aeruginosa ATCC 27833.