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Molecular docking and dynamics simulation study of bioactive compounds from Aloe vera targeting PDE-4 in psoriasis therapy

The immune-mediated inflammatory disorder psoriasis is a common chronic skin disease characterized by hyperactivity of phosphodiesterase-4 (PDE4), leading to the reduction in cAMP levels and overexpression of pro-inflammatory cytokines. Even though Aloe vera has been used for a long time as a dermatological therapeutic agent, there is still scarcity of scientific evidence regarding its anti-psoriatic phytochemicals.

Details
Role Supervisor
Class / Degree Bachelor
Students

Md. Nur Alam

Start Date January, 2025
End Date December, 2025