Dr. Chanchal Mandal
Associate Professor

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Dr. Mandal is currently working as Associate Professor in Biotechnology and Genetic Engineering Discipline, Khulna University where he is working since 2018. After earning his bachelor degree from the same department he joined Professor Chai's Laboratory in Hanyang University, Republic of Korea to pursue his MS leading PhD degree. After successful completion of his doctoral research he was assigned as a post doctoral research fellow in the same university. He was hired by Professor Oh as a Research Professor in Korea University, Republic of Korea. In Khulna University Dr. Mandal has contributed toward lecturing in undergrad and MS courses, thesis supervision and other relevant academic and non academic responsibilities. He was also assigned as a guest reviewer in some reputed international journals related to his research fields.

Doctor of Philosophy: (Integrated Master’s and Doctoral Program)

                                       Major: Molecular and Life Science

                                       Department of Molecular and Life Sciences

                                       Hanyang University

                                       Republic of Korea

 

Bachelor of Science:

                                       Major: Biotechnology & Genetic Engineering

                                       Life Science School

                                       Khulna University

                                       Bangladesh

 

Higher Secondary Certificate:

                                       Group: Science

                                       Notre Dame College, Dhaka

                                       Dhaka Board

                                       Bangladesh

 

Secondary School Certificate:

                                       Group: Science

                                       Swarupkathi Collegiate Academy, Pirojpur

                                       Jessore Board

                                       Bangladesh

Developmental Biology, Toxicology, Genomics and Epigenomics, Drug Discovery

Current Research Project/Collaboration

SL Title Research Role Awarded Date Completion Date Funding Agency
1 Presence of toxic heavy metals in the maternal blood: A gestational quantification Principal Investigator March 11, 2021 November, 2022 National
2 Comparative assessment of heavy metals present in amniotic fluid and meconium: Bangladesh perspectives Principal Investigator January, 2023 April, 2025 National
3 Evaluation of High Predictive C-reactive Protein (CRP) in Pregnancy and Its Correlation with Pregnancy-related Complications: A Clinical Observational Study in Different Hospitals in Khulna, Bangladesh Co-Principal Investigator November, 2021 September, 2023 National

Research Professor:        Department of Medical Science

                                           Institute of Human Genetics

                                           Korea University

                                           Republic of Korea

 

Postdoctoral Research Fellow:

                                           Institute of Natural Science and Technology

                                           Hanyang University

                                           Republic of Korea

 

Doctoral Researcher:      Department of Molecular and Life Sciences

                                           Hanyang University

                                           Republic of Korea

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30. Preety SS, Tasin FR, Sarder A, Halder D, Yasmin F, Mandal C. Molecular signature of cadmium-mediated neurodevelopmental disorders in prenatal to postnatal stages. EXCLI journal. 2025 Jul 17;24:797. DOI: 10.17179/excli2025-8322


29. Preety SS, Yasmin F, Sarder A, Tasin FR. and Mandal C*. The Status of Heavy Metal Contamination in Amniotic Fluid and Meconium in Khulna City, Bangladesh: A Cross-Sectional Study. Journal of Biological Research and Reviews. 2025 2(3), pp.155-155. DOI: 10.5455/JBRR.20250327073713


28. Sarder A, Mandal C. Amphiphilic Nanocarriers to Fight Against Pathogenic Bacteria. In Recent Trends and The Future of Antimicrobial Agents - Part 2 2023 (pp. 76-100). Bentham Science. https://doi.org/10.2174/9789815123975123010007


27. Mandal C*, Tasin FR, Haque N. Secondary Metabolites from Plant Endophytes: Possible Source of Future Antimicrobial Compounds. In Recent Trends and The Future of Antimicrobial Agents - Part I 2023 (pp. 93-139). Bentham Science. https://doi.org/10.2174/9789815079609123010007


26. Sarder A, Mia MB, Sarkar A, Mandal C*. Immune Checkpoint Inhibitor Therapy in Cancer: Success versus Limitations. Biomedical Research and Therapy. 2022 Dec 31;9(12):5455-64. DOI : 10.15419/bmrat.v9i12.784


25. Tasin FR, Haque N, Mandal C*. Antibodies as Antibacterial Molecules: The New Era of Antibody-Mediated Immunity. In Alternatives to Antibiotics 2022 (pp. 83-108). Springer Nature, Singapore. DOI: 10.1007/978-981-19-1854-4_4


24. Tasin FR, Ahmed A, Halder D, Mandal C*. On-going consequences of in utero exposure of Pb: An epigenetic perspective. J Appl Toxicol. 2022 Jan 12. doi: 10.1002/jat.4287


23. Kang MJ, Lee S, Jung U, Mandal C, Park H, Stetler-Stevenson WG, Kim YS, Moon JW, Park SH, Oh J. Inhibition of Hepatic Stellate Cell Activation Suppresses Tumorigenicity of Hepatocellular Carcinoma in Mice. Am J Pathol. 2021 Dec;191(12):2219-2230. doi: 10.1016/j.ajpath.2021.08.004


22. Tasin FR, Halder D, Mandal C. Possible Therapeutic Uses of Extracellular Vesicles for Reversion of Activated Hepatic Stellate Cells: Context and Future Perspectives. Curr Mol Med. 2022;22(2):151-164. doi: 10.2174/1566524021666210218113928


21. Islam A, Mandal C, Habib A. Antibacterial potential of synthesized silver nanoparticles from leaf extract of Moringa oleifera. J Adv Biotechnol Exp Ther. 2021 Jan; 4(1): 67-73. https://doi.org/10.5455/jabet.2021.d108


20. Cha JJ, Mandal C, Ghee JY, Yoo J, Lee MJ, Kang YS, Hyun YY, Lee JE, Kim HW, Han SY, Han JY. Inhibition of Renal Stellate Cell Activation Reduces Renal Fibrosis. Biomedicines. 2020 Oct;8(10):431. doi:10.3390/biomedicines8100431


19. Haque N, Fareez IM, Fong LF, Mandal C, Kasim NH, Kacharaju KR, Soesilawati P. Role of the CXCR4-SDF1-HMGB1 pathway in the directional migration of cells and regeneration of affected organs. World Journal of Stem Cells. 2020 Sep 26;12(9):938. DOI: 10.4252/wjsc.v12.i9.938


18. Mandal C, Yoon T, Park JY, Jung KH, Chai YG. Lipopolysaccharide‑dependent transcriptional regulation of PU.1 in microglial cells. Mol Cell Toxicol. 2019, https://doi.org/10.1007/s13273-019-00057-6.


17. Mandal C, Tabassum T, Shuvo MJ, Habib A. Biochemical and molecular identification of antibiotic-producing bacteria from waste dumpsite soil. J Adv Biotechnol Exp Ther. 2019; 2(3): 120-126. https://doi.org/10.5455/jabet.2019.d34.


16. Mandal C, Kim SH, Chai JC, Lee YS, Jung KH, Chai YG. Gene expression signatures after ethanol exposure in differentiating embryoid bodies. Toxicol In Vitro. 2018 Feb;46:66-76. doi: 10.1016/j.tiv.2017.10.004.

 

15. Mandal C, Halder D, Jung KH, Chai YG. Maternal alcohol consumption and altered miRNAs in the developing fetus: Context and future perspectives. J Appl Toxicol. 2018 Jan;38(1):100-107. doi: 10.1002/jat.3504.

 

14. Mandal C, Kim SH, Kang SC, Chai JC, Lee YS, Jung KH, Chai YG. GSK-J4-Mediated Transcriptomic Alterations in Differentiating Embryoid Bodies. Mol Cells. 2017 Oct;40(10):737-751. doi: 10.14348/molcells.2017.0069.

 

13. Mandal C, Halder D, Jung KH, Chai YG. In Utero Alcohol Exposure and the Alteration of Histone Marks in the Developing Fetus: An Epigenetic Phenomenon of Maternal Drinking. Int J Biol Sci. 2017 Sep 5;13(9):1100-1108. doi: 10.7150/ijbs.21047.

 

12. Mandal C, Halder D, Jung KH, Chai YG. Gestational Alcohol Exposure Altered DNA Methylation Status in the Developing Fetus. Int J Mol Sci. 2017 Jun 28;18(7). doi: 10.3390/ijms18071386.

 

11. Mandal C, Kim SH, Chai JC, Oh SM, Lee YS, Jung KH, Chai YG. RNA Sequencing Reveals the Alteration of the Expression of Novel Genes in Ethanol-Treated Embryoid Bodies. PLoS One. 2016 Mar 1;11(3):e0149976. doi: 10.1371/journal.pone.0149976.

 

10. Mandal C, Halder D, Chai JC, Lee YS, Jung KH, Chai YG. Profiling ethanol-targeted transcription factors in human carcinoma cell-derived embryoid bodies. Gene. 2016 Jan 15;576(1 Pt 1):119-25. doi: 10.1016/j.gene.2015.09.085.

 

9. Mandal C, Park KS, Jung KH, Chai YG. Ethanol-related alterations in gene expression patterns in the developing murine hippocampus. Acta Biochim Biophys Sin (Shanghai). 2015 Aug;47(8):581-7. doi: 10.1093/abbs/gmv050.

 

8. Mandal C, Park JH, Lee HT, Seo H, Chung IY, Choi IG, Jung KH, Chai YG. Reduction of Nfia gene expression and subsequent target genes by binge alcohol in the fetal brain. Neurosci Lett. 2015 Jun 26;598:73-8. doi: 10.1016/j.neulet.2015.05.016.

 

7. Mandal C, Park JH, Choi MR, Kim SH, Badejo AC, Chai JC, Lee YS, Jung KH, Chai YG. Transcriptomic study of mouse embryonic neural stem cell differentiation under ethanol treatment. Mol Biol Rep. 2015 Jul;42(7):1233-9. doi: 10.1007/s11033-015-3862-1.

 

6. Halder D, Mandal C, Lee BH, Lee JS, Choi MR, Chai JC, Lee YS, Jung KH, Chai YG. PCDHB14- and GABRB1-like nervous system developmental genes are altered during early neuronal differentiation of NCCIT cells treated with ethanol. Hum Exp Toxicol. 2015 Oct;34(10):1017-27. doi: 10.1177/0960327114566827.

 

5. Halder D, Park JH, Choi MR, Chai JC, Lee YS, Mandal C, Jung KH, Chai YG. Chronic ethanol exposure increases goosecoid (GSC) expression in human embryonic carcinoma cell differentiation. J Appl Toxicol. 2014 Jan;34(1):66-75. doi: 10.1002/jat.2832.

 

4. Mandal C, Jung KH, Kang SC, Choi MR, Park KS, Chung YI and Chai YG. Knocking down of UTX in NCCIT cells enhance cell attachment and promote early neuronal cell differentiation. BioChip J. 2015, 1-11. doi: 10.1007/s13206-015-9302-4

 

3. Mandal C, Jung KH and Chai YG. Ethanol toxicity affects olfactory receptor genes in forebrain of fetal mice. Mol Cell Toxicol. 2015, 11:55-60. doi: 10.1007/s13273-015-0007-5.

 

2. Mandal C, Baek MN, Jung KH, Chai JC, Lee YS and Chai YG. Gene expression profile associated with the reversine-mediated transdifferentiation of NIH-3T3 fibroblast cells into osteoblasts. BioChip J. 2013, 7(3): 278-287. doi: 10.1007/s13206-013-7311-8

 

1. Alam KS, Khan SA, Seheli K, Huda MN, Wadud MA, Reza MSH, Ali ME, Mandal C, Salam MA. Mosquitocidal activity of Bti producing Cry protein against Aedes aegypti mosquito. Research Journal of Environmental Sciences. 2008; 2(1): 46-51. doi: 10.3923/rjes.2008.46.51