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Pharmacy Discipline, Khulna university , Khulna, Bangladesh
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click herePhytochemical and Pharmacological evaluation of Alysicarpus vaginalis
The project work has been designed to investigate the crude ethanolic
extract of Alysicarpus vaginalis, a shrub belonging to the family
of Fabaceae for its phytochemical nature and selected pharmacological activities
including anti-allergic and anti-hyperglycemic potentials. In order to ascertain the therapeutic uses
of the plant, leaves or whole plant were subjected to explore for phytochemical
nature and selected pharmacological activities. Phytochemical analysis was conducted to reveal major functional
groups in the ethanol extract of the whole plant. This test indicated the presence of combined reducing sugars,
flavonoids, glycosides, gums, saponins, steroids, carbohydrate, acidic
compounds and terpenoids, those will be the reason of claimed activity of plant extract.
In this studies, plant extract
showed a significant anti-allergic activity as well as anti-hyperglycemic activity.
In anti-hyperglycemic test the plant extract was screened and compared with
Glibenclamide standard. The extract was found to reduce the blood glucose level
to a significant extent. Along with anti-allergic activity test extract was
able to decrease significantly TDI induced sneezing, scratching and nasal score
and other allergic symptoms when compared with positive control. Also
significantly increase the total count of WBC and the number of neutrophils, lymphocytes and eosinophils in a dose dependent
manner. Therefore, the present study revealed the anti-hyperglycemic activities
and anti- allergic activity of A. vaginalis which support its folkloric uses
and required further research.
| Details | |||
| Role | Supervisor | ||
|---|---|---|---|
| Class / Degree | Bachelor | ||
| Students | B. Pharm project | ||
| Start Date | January,2020 | ||
| End Date | December, 2020 | ||