Selective adsorption of indole on mesoporous carbon in an aqueous system

Abstract

The removal of uremic toxins, such as indole, using carbon-based adsorbents is essential for preventing the progression of chronic kidney disease (CKD). Mesoporous carbon (MC) with a uniform pore diameter of 3.1 nm was used as an adsorbent for indole in aqueous media. The adsorption kinetics and thermodynamics of MC were examined, with the conventional adsorbent AST-120 serving as a control. Compared to AST-120, MC showed highly efficient indole adsorption and remarkable adsorption selectivity for indole in the presence of various amino acids. The excellent selectivity of MC has the potential to reduce the required dose of the adsorbent, thereby improving treatment strategies for patients with CKD.