Dr. Md. Morsaline Billah
Professor



An enthusiastic and proactive biotechnologist with extensive experience in teaching and research at undergraduate and graduate level students and proficient in theoretical and experimental research activities in allied fields of interest with good expertise on bioprospecting of plant and microbial resources, bionanotechnology, biotechnology business, curriculum design and development having strong interest in educating students and sharing knowledge to broader audience in research and academia. 

  • PhD in Biochemistry and Microbiology (2004-2008), Institute of Membrane and Systems Biology, University of Leeds, Leeds, United Kingdom
  • Bachelor of Science in Biotechnology (1995-1999), Khulna University, Khulna, Bangladesh

  • Visiting Academic and Commonwealth Rutherford Fellow (2018-2020), Lincoln International Business School, University of Lincoln, Brayford Pool, Lincoln, United Kingdom
  • Visiting Researcher and Islamic Development Bank Fellow (2016-2017), Institute of Quantative Biology, Biochemistry and Biotechnology, The University of Edinburgh, United Kingdom
  • Visiting Professor (2013), University of British Columbia, Canada
  • Postdoctoral Research Scientist (2011-2012), Kulliyah of Science, International Islamic University Malaysia (IIUM), Malaysia. 
  • Research Fellow (2008), Institute of Membrane and Systems Biology, University of Leeds, United Kingdom

     

            Google Scholar: https://scholar.google.com/citations?user=YEz6_-YAAAAJ&hl=en

  • Environmental Monitoring by Electro-analytical and Biosensing Techniques (Detection of Heavy Metals in Water and Environmental Samples)
  • Bioprospecting of Mangrove Flora and Endophytic Fungi of The Sundarbans
  • Immunology of Viral Infections and Immunometabolism
  • Healthcare Monitoring by Biosensing Techniques
  • Surface Modification and Functionalisation
  • Biotechnology Business and Entrepreneurship Development.

Current Research Project/Collaboration

SL Title Research Role Awarded Date Completion Date Funding Agency
1 Detection of Pathogens in Drinking Water to Prevent Waterborne Disease Transmission in Developing Countries Principal Investigator 2014 2016 International
2 Bioprospecting the medicinal plants of the Sundarbans, the world’s largest mangrove forest, in search for new medicine Principal Investigator 2013 2019 International
3 Evaluation of Cytotoxic Activity of Mangrove Plants from The Sundarbans and Possible Search for Anticancer Principles Principal Investigator 2016 2019 National
4 More Entrepreneurial Life at Bangladeshi Universities (MELBU) Co-Principal Investigator 2020 2023 International
5 Potential of Honey Production in the Sundarbans Mangrove Forest of Bangladesh and the impact of COVID-19 pandemic on the Honey Collectors in the Region, funded by the Administrative Convention Center at Khulna, Government of Bangladesh Co-Principal Investigator 2022 2023 National
6 Utilization of waste bio-resources for the production of environmental friendly binderless composites to meet the demand of 21st century Co-Principal Investigator 2016 2018 International
7 TRANSFORMWASTE: Transforming liquid waste from rice industries to green bioplastics Co-Principal Investigator 2020 2022 International
8 A Multi-Center Evaluation of the Risk Factors and Disease Fatality for the SARS-CoV-2 in Bangladeshi Population: A Retrospective Study Principal Investigator 2022 2023 International
9 Development and characterization of Chitosan-based Composite Film for Antimicrobial Food Packaging Applications Principal Investigator 2021 2023 National

  • Visiting Academic (2018-2020), Lincoln International Business School, University of Lincoln, United Kingdom
  • Professor ( 2013-), Biotechnology and Genetic Engineering Discipline, Khulna University, Bangladesh
  • Visiting Researcher (2016-2017),  Institute of Quantitative Biology, Biochemistry and Biotechnology, The University of Edinburgh, United Kingdom
  • Visiting Professor (2013), School of Engineering, University of British Columbia, Canada
  • Postdoctoral Researcher (2011-2012), International Islamic University Malaysia (IIUM), Malaysia
  • Associate Professor (2009-2013), Biotechnology and Genetic Engineering Discipline, Khulna University, Bangladesh
  • Research Fellow (2008), Institute of Membrane and Systems Biology, University of Leeds, United Kingdom
  • Assistant Professor (2004-2009), Biotechnology and Genetic Engineering Discipline, Khulna University, Bangladesh
  • Lecturer (2001-2004), Biotechnology and Genetic Engineering Discipline, Khulna University, Bangladesh.

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No.

Author list

Title of the article

Title of the journal

Volume (Issue), Pages

DOI

Year

1

Rafique AA, Sahani A, Billah MM, Islam KMD

Nature's polymer reimagined: Conventional and green routes to pectin, its bioactive promise and industrial applications

Food Chemistry International

Advance online publication

https://doi.org/10.1016/j.fochint.2026.100123

2026

2

Mittra CR, Saha AK, Uddin SJ, Islam MA, Billah MM, Rouf R, Shilpi JA

Ethnomedicinal knowledge of forest-dependent communities in the eastern coastal region of Khulna, Bangladesh

Human Ecology

54(1), 33

https://doi.org/10.1007/s10745-026-00662-9

2026

3

Hossain MA, Islam ME, Rahman SMM, Billah MM

Physicochemical characteristics and bioactive properties of honey from the Sundarbans mangrove forest, Bangladesh

Food Chemistry International

Advance online publication

https://doi.org/10.1016/j.fochint.2026.100899

2026

4

Roshnee FI, Rimi AA, Shubhro K, Chowdhury NR, Anim SMR, Islam KMD, Islam ME, Rahman SMM, Islam A, Billah MM

Isolation, characterization and molecular identification of nitrogen fixing bacteria from rhizosphere of Xylocarpus moluccensis: Nitrogen-fixing bacteria from X. moluccensis

Khulna University Studies

23(1), 94–100

https://doi.org/10.53808/KUS.2026.23.01.1457-ls

2026

5

Hossain HMR, Islam A, Nurunnabi TR, Rahman SMM, Islam ME, Islam KMD, Billah MM

Isolation, identification and characterization of cellulolytic bacteria from agricultural waste residues: Unlocking microbial solutions for organic waste utilization

Khulna University Studies

23(1), 86–93

https://doi.org/10.53808/KUS.2026.23.01.1441-ls

2026

6

Islam MN, Promie AR, Siddika R, Mim SH, Islam MA, Billah MM, … Kubra MK

Nutritional composition, anti-oxidant, anthelmintic and anti-diabetic properties of juice and molasses of Nypa fruticans collected from coastal areas of Bangladesh

Food and Humanity

5, 100692

https://doi.org/10.1016/j.foohum.2025.100692

2025

7

Shaha PR, Rimi AA, Islam A, Mia M, Islam ME, Islam KMD, … Rahman SMM

Therapeutic Potential of Coastal Seaweed: In Vitro Pharmacological Evaluation of Ulva prolifera as a Natural Source of Bioactive Compounds

Thalassas: An International Journal of Marine Sciences

41(4)

https://doi.org/10.1007/s41208-025-00994-1

2025

8

Billah NMA, Khan U, Islam KMD, Abdul-Awal SM, Billah MM

Integrative analysis of Hub1 overexpression: driving transcriptional reprogramming and alternative splicing in Saccharomyces cerevisiae

BMC Genomics

26(1)

https://doi.org/10.1186/s12864-025-12006-w

2025

9

Shubhro K, Rimi AA, Mia M, Islam ME, Islam KMD, Billah MM, Rahman SMM

Therapeutic Prospects of Actinomycetes Derived Metabolites Isolated from Coastal Sediments

Microbiology and Biotechnology Letters

53(3), 417–429

https://doi.org/10.48022/mbl.2504.04014

2025

10

Refat MKH, Nishi FA, Shubhro K, et al.

Effects of Ultrasound-Assisted Extraction on Physicochemical and Functional Properties of Gelatin Derived from Hilsha (Tenualosa ilisha) Scales

Food Biophysics

20, 14

https://doi.org/10.1007/s11483-024-09903-0

2025

11

Nahar N, Zilani MNH, Biswas P, Billah MM, Bibi S, Albekairi NA, Alshammari A, Hasan MN

Profiling of secondary metabolite and evaluation of anti-diabetic potency of Crotalaria quinquefolia (L): In-vitro, in-vivo, and in-silico approaches

Saudi Pharmaceutical Journal*

32(1), 101887

https://doi.org/10.1016/j.jsps.2023.101887

2024

12

Saha P, Billah MM, Islam ABMN, Habib MA, Mahiuddin M

Green synthesized silver nanoparticles: a potential antibacterial agent, antioxidant, and colorimetric nanoprobe for the detection of Hg²⁺ ions

Global Challenges

7(8), 2300072

https://doi.org/10.1002/gch2.202300072

2023

13

Khan AM, Sharif MA, Salekeen R, Rahman MH, Mahmud S, Biswas P, Hasan MN, Islam KMD, Islam ME

In vitro and in silico investigation of garlic's (Allium sativum) bioactivity against 15-lipoxygenase mediated inflammopathies

Journal of Herbmed Pharmacology

12(2), 283–298

https://doi.org/10.34172/jhp.2023.31

2023

14

Islam MN, Das AK, Billah MM, Rahman KS, Hiziroglu S, Hattori N, Agar DA, Rudolfsson M

Multifaceted laser applications for wood – A review from properties analysis to advanced products manufacturing

Lasers in Manufacturing and Materials Processing

10, 225–250

https://doi.org/10.1007/s40516-023-00204-x

2023

15

Ashrafy A, Liza AA, Islam MN, Billah MM, Arafat ST, Rahman MM, Rahman SM

Microplastics Pollution: A Brief Review of Its Source and Abundance in Different Aquatic Ecosystems

Journal of Hazardous Materials Advances

9, 100215

https://doi.org/10.1016/j.hazadv.2022.100215

2023

16

Arifuzzaman M, Masud MK, Ahmed A, Billah MM, Islam MN

Electrochemical Biosensors for Cancer Biomarkers Detection

Current Cancer Biomarkers (book chapter), Bentham Science

Not available

https://doi.org/10.2174/9789815079364123010017

2023

17

Mahmud S, Islam KMD, Billah MM, Rahman SMM, Biswas R, Islam ME

Evaluation of Antioxidant and Anticoagulation Activity of Piper chaba Hunter Stem

Pharmaceutical and Biomedical Research

8(2), 113–120

https://doi.org/10.18502/pbr.v8i2.11025

2022

18

Salekeen R, Abu Nasim Haider AN, Akhter F, Billah MM, Islam ME, Islam KMD

Lipid oxidation in pathophysiology of atherosclerosis: Current understanding and therapeutic strategies

International Journal of Cardiology Cardiovascular Risk and Prevention

14, 200143

https://doi.org/10.1016/j.ijcrp.2022.200143

2022

19

Pervin R, Nurunnabi TR, Biswas R, Islam ME, Islam KD, Sharif DI, Billah MM, Sabrin F

Assessment of Antioxidant, Antibacterial, and Preliminary Cytotoxic Properties of Brownlowia tersa

Journal of Herbs, Spices & Medicinal Plants*

Not available

https://doi.org/10.1080/10496475.2022.2077878

2022

20

Das AK, Islam MN, Akter A, Promie AR, Billah MM, Akanda MJH

Natural Fiber-based Nanocomposites as Corrosion Inhibitors

In: Verma C, Hussain CM, Ebenso E (Eds.), Anticorrosive Nanomaterials: Future Perspectives (book chapter), Royal Society of Chemistry. ISBN 978-1-83916-411-8

pp. 191–206

https://doi.org/10.1039/9781839166259-00191

2022

21

Babu MM, Akter S, Rahman M, Billah MM, Hack-Polay D

The Role of Artificial Intelligence in Shaping the Future of Agile Fashion Industry

Production Planning & Control

Accepted (volume and pages not given)

https://doi.org/10.1080/09537287.2022.2060858

2022

22

Khan U, Habibur Rahman M, Salauddin Khan M, Hossain MS, Billah MM

Bioinformatics and network-based approaches for determining pathways, signature molecules, and drug substances connected to genetic basis of schizophrenia etiology

Brain Research

1785, 147889

https://doi.org/10.1016/j.brainres.2022.147889

2022

23

Mahmud-Al-Rafat A, Hewins B, Mannan A, Kelvin DJ, Billah MM

COVID-19 vaccine inequity, dependency, and production capability in low-income and middle-income countries: the case of Bangladesh

The Lancet Infectious Diseases

Advance online publication

https://doi.org/10.1016/S1473-3099(22)00028-7

2022

24

Salekeen R, Siam M, Sharif DI, Lustgarten MS, Billah MM, Islam K

In silico insights into potential gut microbial modulation of NAD+ metabolism and longevity

Journal of Biochemical and Molecular Toxicology

35(12), e22925

https://doi.org/10.1002/jbt.22925

2021

25

Salekeen R, Diaconeasa AG, Billah MM, Islam K

Energy Metabolism Focused Analysis of Sexual Dimorphism in Biological Aging and Hypothesized Sex-specificity in Sirtuin Dependency

Mitochondrion

60, 85–100

https://doi.org/10.1016/j.mito.2021.07.007

2021

26

Khan U, Chowdhury S, Billah MM, Islam KMD, Thorlacius, Rahman M

Neutrophil Extracellular Traps in Colorectal Cancer Progression and Metastasis

International Journal of Molecular Sciences

22, 7260–7278

https://doi.org/10.3390/ijms22147260

2021

27

Das AK, Islam MN, Billah MM, Sarker A

COVID-19 and municipal solid waste (MSW) management: a review

Environmental Science and Pollution Research

28, 28993–29008

https://doi.org/10.1007/s11356-021-13914-6

2021

28

Rahman KMT, Islam MF, Saha S, Billah MM

The Central Importance of Hub Proteins in a Disease-Gene Network Model: A New Paradigm of Chronic Myeloid Leukemia Disease Study

bioRxiv (preprint)

Not applicable

https://doi.org/10.1101/2021.03.21.436331

2021

29

Das AK, Islam MN, Billah MM, Sarker A

COVID-19 pandemic and healthcare solid waste management strategy – A mini-review

Science of the Total Environment

778, 146220

https://doi.org/10.1016/j.scitotenv.2021.146220

2021

30

Islam T, Islam MN, Zzaman W, Billah MM

Study of Antimicrobial, Antioxidant and Cytotoxicity Properties of Selected Plant Extracts for Food Preservative Applications

International Journal of Food Studies

10, 95–111

https://doi.org/10.7455/ijfs/10.SI.2021.a8

2021

31

Salekeen R, Barua J, Shaha PR, Islam KMD, Islam ME, Billah MM, Rahman SMM

Marine phycocompound screening reveals a potential source of novel senotherapeutics

Journal of Biomolecular Structure and Dynamics

Not available

https://doi.org/10.1080/07391102.2021.1877822

2021

32

Salekeen R, Ahmed A, Islam ME, Billah MM, Rahman H, Islam KMD

In-silico screening of bioactive phytopeptides for novel anti-ageing therapeutics

Journal of Biomolecular Structure and Dynamics

Not available

https://doi.org/10.1080/07391102.2020.1859411

2020

33

Nurunnabi TR, Sarwar S, Sabrin F, Alam F, Nahar L, Sohrab H, Sarker SD, Rahman SMM, Billah MM

Molecular identification and antimicrobial activity of endophytic fungi isolated from Heritiera fomes (Buch.-Ham), a mangrove plant of the Sundarbans

Beni-Suef University Journal of Basic and Applied Sciences

9, 61

https://doi.org/10.1186/s43088-020-00081-9

2020

34

Salekeen R, Mou SN, Islam ME, Ahmed A, Billah MM, Rahman SMM, Islam KMD

Predicting multi-enzyme inhibition in the arachidonic acid metabolic network by Heritiera fomes extracts

Journal of Biomolecular Structure and Dynamics

Not available

https://doi.org/10.1080/07391102.2020.1855248

2020

35

Mahmud-Al-Rafat A, Asim MMH, Taylor-Robinson AW, Majumder A, Muktadir A, Muktadir H, Karim M, Khan I, Ahasan MM, Billah MM

A combinational approach to restore cytokine balance and to inhibit virus growth may promote patient recovery in severe COVID-19 cases

Cytokine

136, 155228

https://doi.org/10.1016/j.cyto.2020.155228

2020

36

Rahman M, Billah MM, Hack-Polay D, Alam A

The use of biotechnologies in textile processing and environmental sustainability: An emerging market context

Technological Forecasting and Social Change

159, 120204

https://doi.org/10.1016/j.techfore.2020.120204

2020

37

Hack-Polay D, Rahman M, Billah MM, Al-Sabbahy HZ

Big data analytics and sustainable textile manufacturing: Decision-making about the applications of biotechnologies in developing countries

Management Decision

58(8), 1699–1714

https://doi.org/10.1108/MD-09-2019-1323

2020

38

Rahman M, Hack-Polay D, Billah MM, Nabi NU

Bio-based textile processing through the application of enzymes for environmental sustainability

International Journal of Technology Management and Sustainable Development

19(1), 87–106

https://doi.org/10.1386/tmsd_00017_1

2020

39

Nurunnabi TR, Sabrin F, Sharif DI, Nahar L, Sohrab MH, Sarker SD, Rahman SMM, Billah MM

Antimicrobial activity of endophytic fungi isolated from the mangrove plant Sonneratia apetala (Buch.-Ham) from the Sundarbans mangrove forest

Advances in Traditional Medicine

20, 419–425

https://doi.org/10.1007/s13596-019-00422-9

2020

40

Aunjum A, Biswas R, Ullah M, Billah MM, Islam ME, Islam KMD

Bioactivity analysis of Sarcolobus globosus Wall., a mangrove plant of the Sundarbans

Journal of the Bangladesh Agricultural University

17(4), 476–482

https://doi.org/10.3329/jbau.v17i4.44608

2019

41

Biswas R, Rahman SMM, Islam KMD, Billah MM, Aunjum A, Nurunnabi TR, Kundu SK, Islam ME

Antioxidant, Anti-inflammatory, and Anticoagulation Properties of Aegiceras corniculatum and Acanthus ilicifolius

Pharmaceutical and Biomedical Research

5(3), 35–44

https://doi.org/10.18502/pbr.v5i3.2117

2019

42

Aunjum A, Biswas R, Nurunnabi TR, Rahman SMM, Islam ME, Islam KMD

Antioxidant and antibacterial activity of three herbs belonging to Zingiber genus of Bangladesh

Advances in Traditional Medicine

20, 343–350

https://doi.org/10.1007/s13596-019-00403-y

2019

43

Islam ME, Islam KMD, Billah MM, Biswas R, Sohrab MH, Rahman SMM

Antioxidant and anti-inflammatory activity of Heritiera fomes (Buch.-Ham), a mangrove plant of the Sundarbans

Oriental Pharmacy and Experimental Medicine

Not available

https://doi.org/10.1007/s13596-019-00401-0

2019

44

Rahman M, Billah MM, Hack-Polay D

What is hindering change? Anticipating the barriers to the adoption of enzyme-based textile processing in a developing country

Business Strategy and Development

Early View

https://doi.org/10.1002/bsd2.58

2019

45

Mahmud-Al-Rafat A, Majumder A, Taufiqur Rahman KM, Mahedi Hasan AM, Islam KMD, Taylor-Robinson AW, Billah MM

Decoding the enigma of antiviral crisis: Does one target molecule regulate all?

Cytokine

115, 13–23

https://doi.org/10.1016/j.cyto.2018.12.008

2019

46

Islam MT, Ali ES, Uddin SJ, Shaw S, Islam MA, Ahmed MI, Chandra Shill M, Karmakar UK, Yarla NS, Khan IN, Billah MM, et al.

Phytol: A review of biomedical activities

Food and Chemical Toxicology*

121, 82–94

https://doi.org/10.1016/j.fct.2018.08.032

2018

47

Nurunnabi TR, Al-Majmaie S, Nakouti I, Nahar L, Rahman SMM, Sohrab MH, Billah MM, et al.

Antimicrobial activity of kojic acid from endophytic fungus Colletotrichum gloeosporioides isolated from Sonneratia apetala, a mangrove plant of the Sundarbans

Asian Pacific Journal of Tropical Medicine

11, 350–354

https://doi.org/10.4103/1995-7645.233183

2018

48

Nurunnabi TR, Nahar L, Al-Majmaie S, Rahman SMM, Sohrab MH, Billah MM, Ismail FMD, Rahman MM, Sharples GP, Sarker SD

Anti-MRSA activity of oxysporone and xylitol from the endophytic fungus Pestalotia sp. growing on the Sundarbans mangrove plant Heritiera fomes

Phytotherapy Research

32, 348–354

https://doi.org/10.1002/ptr.5983

2018

49

Islam MR, Mondol OK, Rahman MS, Billah MM, Rahman MS, Zohora US

Screening of α-amylase producing bacteria from tannery wastes of Hazaribag, Bangladesh

Jahangirnagar University Journal of Biological Sciences

5, 1–10

https://doi.org/10.3329/jujbs.v5i2.32511

2016

50

Afrin S, Pervin R, Sabrin F, Sohrab MH, Rony SR, Islam ME, Islam KD, Billah MM

Assessment of antioxidant, Antibacterial and preliminary cytotoxic activity of chloroform and methanol extracts of Caesalpinia crista L. leaf

Bangladesh Journal of Botany

45, 1061–1068

Not available

2016

51

Afrin S, Pervin R, Sabrin F, Sohrab MH, Rony SR, Islam ME, Islam KD, Billah MM

In vitro antioxidant activity, antimicrobial and preliminary cytotoxic activity of Cynometra ramiflora – a mangrove plant

Journal of Microbiology, Biotechnology and Food Sciences

6, 844–850

https://doi.org/10.15414/jmbfs.2016.6.2.844-850

2016

52

Islam T, Khan IH, Afroz KF, Rahman MZ, Hossain MS, Islam ME, Billah MM, Islam KD

Effective identification of Lactobacillus paracasei ssp. paracasei-1 by 16S-23S rRNA intergenic spacer region sequencing

Journal of Microbiology, Biotechnology and Food Sciences

6, 702–706*

https://doi.org/10.15414/jmbfs.2016.6.1.695-701

2016

53

Akter M, Afrin S, Sakib SN, Biswas R, Billah MM, Rahman MS, Zohora US

Investigation of antibacterial, cytotoxic and antioxidant properties of the mangrove plant Xylocarpus mekongensis

Advances in Bioscience and Biotechnology

7, 205–213

https://doi.org/10.4236/abb.2016.74019

2016

54

Pervin R, Afrin S, Sabrin F, Zohora US, Rahman MS, Islam KD, Billah MM

Antioxidant, Antibacterial and Brine Shrimp Lethality Bioassay of Amoora cucullata, a Mangrove Plant

Journal of Young Pharmacists

8(1), 33–38

https://doi.org/10.5530/jyp.2016.1.8

2016

55

Rony IK, Baten A, Bloomfield JA, Islam ME, Billah MM, Islam KD

Inducing pluripotency in vitro: recent advances and highlights in induced pluripotent stem cells generation and pluripotency reprogramming

Cell Proliferation

48(2), 140–156

https://doi.org/10.1111/cpr.12162

2015

56

Sahabuddin M, Ali H, Miah MF, Ferdous A, Akhter MS, Billah MM, Hassan Z, Ali L

Association of vitamin D receptor gene Apa1 (G>T) and Taq1 (T>C) polymorphisms in the pathogenesis of impaired glucose tolerance in subjects of Bangladeshi origin

International Journal of Green and Herbal Chemistry

4(3), 357–369

Not available

2015

57

Honi U, Sabrin F, Islam T, Islam ME, Billah MM, Islam KD

Enzymatic activity and antibiotic resistance profile of Lactobacillus paracasei ssp. paracasei-1 isolated from regional yogurts of Bangladesh

Journal of Microbiology, Biotechnology and Food Sciences

3(3), 235–239

Not available

2013

58

Saha S, Shilpi JA, Mandal H, Gofur MR, Billah MM, Nahar L, Sarker SD

Bioactivity studies on Musa seminifera Lour.

Pharmacognosy Magazine

9, 315–322

https://doi.org/10.4103/0973-1296.117827

2013

59

Billah MM, Hays HCW, Hodges C, Ponnambalam S, Vohra R, Millner PA

Mixed self-assembled monolayer (mSAM) based impedimetric immunosensors for cardiac troponin I (cTnI) and soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1)

Sensors and Actuators B: Chemical

173, 361–366

https://doi.org/10.1016/j.snb.2012.07.017

2012

60

Pervin R, Sabrin F, Billah MM, Islam KMD, Elmezughi J, Shilpi JA

Antibacterial and cytotoxic activity of Meyna spinosa stem

Turkish Journal of Pharmaceutical Sciences

9(2), 225–230

Not available

2012

61

Chowdhury A, Hossain MN, Mostazir NJ, Fakruddin M, Billah MM, Ahmed MM

Screening of Lactobacillus spp. from buffalo yoghurt for probiotic and antibacterial activity

Journal of Bacteriology and Parasitology

3(8), 156–161

https://doi.org/10.4172/2155-9597.1000156

2012

62

Shilpi JA, Islam ME, Billah M, Islam KMD, Sabrin F, Uddin SJ, Nahar L, Sarker SD

Antinociceptive, Anti-Inflammatory, and Antipyretic Activity of Mangrove Plants: A Mini Review

Advances in Pharmacological Sciences

2012, Article ID 576086 (7 pages)

https://doi.org/10.1155/2012/576086

2012

63

Billah MM, Hodges C, Hays HCW, Millner PA

Directed immobilisation of reduced antibody fragments onto a novel SAM on gold for myoglobin impedance immunosensing

Bioelectrochemistry

80(1), 49–54

https://doi.org/10.1016/j.bioelechem.2010.08.005

2010

64

Hoque MZ, Akter F, Hossain KM, Rahman MSM, Billah MM, Islam KMD

Isolation, Identification and Analysis of Probiotic properties of Lactobacillus Spp. from selective regional yoghurts

World Journal of Dairy & Food Sciences

5(1), 39–46

Not available

2010

65

Millner PA, Hays HCW, Vakurov A, Pchelintsev NA, Billah MM, Rodgers MA

Nanostructured transducer surfaces for electrochemical biosensor construction—Interfacing the sensing component with the electrode

Seminars in Cell & Developmental Biology

20, 34–40

https://doi.org/10.1016/j.semcdb.2009.01.011

2009

66

Millner P, Vakurov A, Hays H, Pchelintsev N, Billah M, Rodger M, Gibson T

The nanoscale design of surfaces for building biosensors

Journal of Biotechnology

131(2), S127–S128

https://doi.org/10.1016/j.jbiotec.2007.07.223

2007

67

Roberts LC, Hug SJ, Ruettimann T, Billah M, Khan AW, Rahman MT

Arsenic removal with iron (II) and iron (III) in waters with high silicate and phosphate concentrations

Environmental Science & Technology

38(1), 307–315

https://doi.org/10.1021/es0343205

2004

68

Ahasan MM, Billah MM, Hasan MM, Islam KMD, Shilpi JA

Transmission, biochemical manifestation and CD4+ cell count of HIV: a review

Pakistan Journal of Biological Sciences

7(2), 292–300

https://doi.org/10.3923/pjbs.2004.292.300

2004

69

Shilpi JA, Uddin SJ, Rouf R, Billah MM

Central nervous system depressant activity of Diospyros peregrina bark

Oriental Pharmacy and Experimental Medicine

4(4), 249–252

Not available

2004

70

Ahamed T, Hossain KM, Billah MM, Islam KMD, Ahasan MM, Islam ME

Adaptation of Newcastle disease virus (NDV) on Vero cell line

International Journal of Poultry Science

3(2), 153–156

https://doi.org/10.3923/ijps.2004.153.156

2004

71

Mamun MM, Billah MM, Ashek A, Ahasan MM, Hossain MJ, Sultana T

Evaluation of Diuretic Activity of Ipomoea aquatica (Kalmisak) in Mice Model Study

Journal of Medical Sciences

3(5), 395–400

https://doi.org/10.3923/jms.2003.395.400

2003

72

Islam KMD, Ahamed T, Ahasan MM, Billah MM, Islam ME, Hossain KM

Adaptation of Reovirus on Vero Cell Line

Journal of Animal and Veterinary Advances

2(8), 425–429

No DOI (publisher page: medwelljournals.com/abstract/?doi=javaa.2003.425.429)

2003

73

Shrestha P, Ahasan MM, Islam KMD, Billah MM, Islam ME, Mehedi M, Mitra S, Islam MR

Sero-prevalence of Infectious Bursal Disease Virus (IBDV) Specific Antibody in Chicken

Pakistan Journal of Biological Sciences*

6(14), 1234–1240

https://doi.org/10.3923/pjbs.2003.1234.1240

2003

74

Aryal P, Hossain KM, Ahasan MM, Islam KMD, Billah MM, Islam ME, Mehedi M, Mitra S

Sero-prevalence of Newcastle Disease Virus (NDV) Specific Antibody in Chicken

Journal of Animal and Veterinary Advances

2(6), 366–371

No DOI (publisher page: medwelljournals.com/abstract/?doi=javaa.2003.366.371)

2003

 

Environmental Biotechnology and Genetic Engineering

Please refer to the file link for additional information

Microbial Biotechnology and Genetic Engineering

Please refer to the link

Food Biotechnology

Please refer to the file link for details. 

Medical and Pharmaceutical Biotechnology

Please refer to link for additional information. 

Running

Animal Cell Culture

Please refer to the link for additional information

Biobusiness and Entrepreneurship

Course Contents

CLOs

Section A

1

Innovation and entrepreneurship in bio-business: Introduction and scope in Bio-entrepreneurship, Types of bio-industries and competitive

dynamics between the sub-industries of the bio-sector (e.g., pharmaceuticals vs. Industrial biotech), Strategy and operations of bio-sector firms: Factors shaping opportunities for innovation and entrepreneurship in bio-sectors, and the business implications of those opportunities, Alternatives faced by emerging bio-firms and the relevant tools for strategic decisions, Entrepreneurship development programs of public and private agencies, strategic dimensions of patenting & commercialization strategies.

1, 2

2

Bio markets: Negotiating the road from lab to the market (strategies and processes of negotiation with financiers, government and regulatory authorities), Pricing strategy, Challenges in marketing in bio business (market conditions & segments; developing distribution channels, the nature, analysis and management of customer needs), Basic contract principles, different types of agreement and contract terms typically found in the joint venture and development agreements, Dispute resolution skills.

1, 2, 3

3

Business Strategy: Entry and exit strategy; negotiations with financers, bankers, government and law enforcement authorities; external environment/ changes; avoiding/managing crisis; broader vision–global thinking; mergers & acquisitions.

1, 2

4

Marketing: Market conditions, segments, prediction of market changes; identifying needs of customers; Market linkages, branding issues; developing distribution channels - franchising; policies, promotion, advertising; branding and market linkages for ‘virtual start-up company

3, 4

Section B

CLOs

5

Basics of bioentrepreneurship: Importance of entrepreneurship; advantages of being an entrepreneur-freedom to operate; introduction to bio entrepreneurship-biotechnology on a global scale; Scope in bioentrepreneurship; types of bio-industries – biopharma, bioagri, bioservices and bioindustrial; innovation – types, out of box thinking; skills for successful entrepreneur– creativity, leadership, managerial, team building, decision making; patent landscape, IP protection & commercialization strategies

1, 2, 3

6

Finance and accounting: Business plan preparation including statutory and legal requirements, Business feasibility study, financial management issues of procurement of capital and management of costs, Collaborations & partnership, Information technology

1, 3

7

Technology Management: Technology – assessment, development & upgradation, managing technology transfer, Quality control & transfer of foreign technologies, Knowledge centers and Technology transfer agencies, Understanding of regulatory compliances and procedures (CDSCO, NBA, GCP, GLA, GMP)

1, 2

Running

Biosafety, Bioethics and Intellectual Property Rights

Course Contents

CLOs

Section A

1

Biosafety and Biosecurity: Definition and necessity of biosafety, biosecurity and bioethics; General principles and consideration relevant to risk assessment and management; Biological safety cabinets; primary containment for biohazards; biosafety levels; GRAS organisms, biosafety levels of specific microorganisms; recommended biosafety levels for infectious agents and infected animals. Environmental risk assessment and food and feed safety assessment.

1

2

National and International Regulations: Biosafety guidelines and/regulations of Bangladesh and some other countries; National Committee on Biosafety (NCB), Biosafety Core Committee (BCC), Institutional Biosafety Committee (IBC) and Field Level Biosafety Committee (FBC). Cartagena protocol, OECD consensus documents and Codex Alimentarius. General principles of risk assessment, methodology of risk assessment, criteria for risk assessment, use of GMOs and LMOs in the field, foreign GMOs and LMOs into the environment, industrial use of GMOs.

1, 3

3

Bioethics: Introduction, ethical conflicts in biological sciences - interference with nature, bioethics in health care - “DNA Act 2014” of Bangladesh, patient confidentiality, informed consent, euthanasia, artificial reproductive technologies, prenatal diagnosis, genetic screening, gene therapy, transplantation. Bioethics in research – cloning and stem cell research, Human and animal experimentation, animal rights/welfare, Agricultural biotechnology – Genetically engineered food, environmental risk, labelling and public opinion. Sharing benefits and protecting future generations - Protection of environment and biodiversity – biopiracy.

2, 3

Section B

CLOs

4

Introduction to IPR: Introduction to intellectual property; types of IP: patents, trademarks, copyright & related rights, industrial design, traditional knowledge, geographical indications, protection of new GMOs; International framework for the protection of IP; IP as a factor in R&D; IPs of relevance to biotechnology and few case studies; introduction to history of GATT, WTO, WIPO and TRIPS; plant variety protection and farmers rights act; concept of ‘prior art’: invention in context of “prior art”; patent databases - country-wise patent searches (USPTO, EPO); analysis and report formation.

2

5

Patents, Patent Laws and Management: Types of patents, Patent Cooperation Treaty (PCT) and implications; procedure for filing a PCT application. Time frame and cost, status of the patent applications, precautions while patenting, disclosure/nondisclosure, financial assistance for patenting, introduction to existing schemes. Patent licensing and agreement. Basic, principles and general requirements of patent law. Biotechnological inventions and patent law. Patent infringement- meaning, scope, litigation, case studies. and examples.

2, 3

6

Organs Transplantation: Organ transplantation in human beings, ethics in xenotransplantation, bioethical issues.

3

Running

Biotechnology: Concepts and Applications

Course Contents

CLOs

Section A

1

Introduction to Biotechnology: Definition, history, multidisciplinary nature, scope and avenues of biotechnology, discourse on biotechnology controversy

1, 2, 3

2

Recombinant DNA and “omics” technology: Recombinant DNA technology, cloning, expression, genomics, transcriptomics, proteomics, metabolomics, application of omics

1, 2, 3

3

Microbial biotechnology: Microbes as a tool, microbial fermentation and fermented products, microbial biotechnology in industry, bioterrorism

1, 2, 3

4

Medical and pharmaceutical biotechnology: Animal models of human diseases, biotechnology-enabled diagnosis approaches, biopharmaceuticals, gene therapy and regenerative medicine, vaccine technology

1, 2, 3

Section B

CLOs

5

Agricultural biotechnology: Use of biotechnology in selective breeding, plant tissue culture, genetic engineering of plants, biofertilizer, biopharming, animal cloning, animal cell culture, transgenic animals

1, 2, 3

6

Environmental Biotechnology: Biotechnology and environment, bioremediation, bioleaching, biotransformation, wastewater treatment, biopesticide, environmental risk of biotechnology.

1, 2, 3

7

Entrepreneurship in Biotechnology: Innovation, the fourth industrial revolution, intellectual property right, capital management, biobusiness, biobusiness incubator, entrepreneurship concepts

1, 2, 3

8

Ethical and safety issues in biotechnology: Ethics, crosstalk of biotechnology with ethics, biosafety and biosecurity, ethics and safety in the age of omics

1, 2, 3

Running

Regulatory Framework in Pharmaceutical Industry

Course Contents

CLOs

Section A

11

Introduction to QC and QA: Good Practices in QC laboratory, Schedule L1, standardization of reagents, labelling of reagents, control samples, controls on the animal house, data generation and storage, QC documentation, LIMS Sampling Techniques, Sampling Plans, and Good warehousing practices. Pest and rodent controls; Temperature mapping and monitoring of warehouses; Good Distribution Practices, Waste disposal, disposal procedures and records, and current regulations for waste disposal.

1, 2

22

Quality Management Models: Total Quality Management and its importance to improving business performance; Quality models in business, Six Sigma Concept, Six Sigma tools, Continuous improvements and its applications, Lean Concept for Process improvements.

1, 2, 3

33

Policies and guidelines: ISO 9001/ ISO 13485 standards and their implementation, Quality-Related Guidelines, Legislations and Regulations, PIC guidelines for GMP, Schedule L1, EU guidelines for GMP, WHO GMP guidelines, Canadian GMP Guidelines, Regulatory requirements by different countries, Consumer Protection Act Environment Protection Act, Factories Act, Packaged commodities Act, Import/Export policy; Requirements for import and export of Excipients, Drug substances and Drug Products / Devices.

1, 2

44

Product and facility design and life cycle implementation: Designing of manufacturing facilities for Excipients, API, Drug Formulations, and Medical Devices; ISPE Baseline guidelines; Designing requirements for HVAC systems; Quality -Planning in the Product Life cycle; Product Quality Life cycle implementation (PQLI); In-process quality control on various dosage forms- Sterile and non-sterile; Packaging and labelling controls.

3, 4

55

Current industry status and recalls: Contract manufacturing and analysis, Present status and scope of the pharmaceutical industry in Bangladesh; Analytical Method Transfers; Complaints handling; Root cause analysis; Keppener Trego technique for investigations; Establishment of CAPA; Handling of Recall and recall procedures; Mock recalls.

5

Section B

CLOs

6

Biomanufacturing principles: Overview and design of biomanufacturing, quality by design approach, technical considerations, phases and scale up: life cycle of manufacturing, raw material considerations, compliance and quality in biomanufacturing, lean biomanufacturing; Process analytical technology (PAT) during biomanufacturing: background and need tools for data acquisitions (software in fermenters, flow filtrations, chromatography, analysis and design process analyzers, process control tools and continuous improvement and knowledge management; Standard manufacturing operating procedures of biotechnology, including upstream and downstream processing of proteins, and quality control of protein production, and final fill and finish of product; Case studies to be included: therapeutic proteins, monoclonal antibodies, human vaccines.

1, 2, 3

77

Quality System: Introduction to quality system, main elements of a quality system; Essential of the quality system; Practical implementation of a quality system; Structure of quality manual, correlation between GMP requirements (WHO) and ISO 9001:2000.

1, 3

88

Principles and Practice of GMP: Personnel, Premises, Facilities and Equipment, Pharmaceutical water, Qualification, Process Validation, Cleaning Validation, Production, Sterile Production and Packaging, Documentation.

1, 2

99

GMP in regulation: Information, national bodies and pharmaceutical associations; Pharmacopeia; EU directives and guidelines, USA: CFR and FDA guidelines, ICH-guidelines, PIC/S guidelines, GMP of other regions, WHO guidelines.

4

Research Methodology

Section B

Rapid Rural Appraisal (RRA), Participatory Rural Appraisal (PRA) and Rapid Rural System Appraisal (RRSA). Organization and differences among RRA, PRA and RRSA. 

Ex-ante analysis:  Ex-ante analysis of research design and critical path method for planning and management of project.

Research Law, Monitoring and Evaluation: International and National laws and legislation; objectives, monitoring and evaluation process, typology of evaluation, planning and designing a monitoring and evaluation system, monitoring and evaluation of training programs, writing an evaluation report, term of references, program performance indicators and plan for dissemination of evaluation report.

Literature Review: Purpose and types/sources of review; preparation of index card for reviewing and abstracting; review of scientific reports.

Validity, Reliability and Ethics in Research: Definition, differences between validity and reliability, factors resulting in poor reliability and improvement measures, internal and external validity. Necessities of ethical clearance and its monitoring.  

Annual Reports and Interpretation: Concept, techniques and significance and precautions of interpretation. Types, purpose, format, steps, significance and precautions of writing research report, Salient features of research highlights and executive summary.

Research Systems and its Coordination in Different Sectors of Bangladesh (agriculture, health, industry, fisheries, livestock and universities).


Running

Fermentation Technology and Bioreactor Design

Section – B

5.Transport phenomena in bioprocess systems: Introduction, gas-liquid mass transfer in cellular systems, critical oxygen concentration and oxygen uptake, determination of oxygen transfer rates, mass transfer across free surfaces, surfaces, factor affecting oxygen transfer rates, sterilization of gases and liquids by filtration.

6.Scale up: History, Scale up criteria, Equipments to be scaled up, Scale up Parameters.

7.Instrumentation and control: Introduction, process control, in-line measurements, on-line measurements, computers and interfaces.

8.Bioprocess Economics: Stages in Plant Design, Break even analysis, Depreciation, method of calculation of depreciation, Optimization, Graphical and Mathematical Approaches of Optimization.

Running
  • Environmental Biotechnology and Genetic Engineering
  • Microbial Biotechnology and Genetic Engineering
  • Food Biotechnology
  • Animal Cell Culture
  • Biotechnology: Concepts and Applications
  • Regulatory Framework in Pharmaceutical Industry
  • Fermentation Technology and Bioreactor Design