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Pharm-1101
Pharmacognosy – I
3  Credit

Section -A

  1. Definition, scope and historical development of Pharmacognosy.
  2. Drug literature and publications: Pharmacopoeia, codex, formulary, dispensatory and index, official drugs, non-official drugs, unofficial drugs.
  3. Plants in complimentary and traditional systems of medicines: Introduction, different types of alternative systems of treatments: Ayurvedic, Unani & Homeopathic medicine; contribution of traditional drugs to modern medicines,
  4. Details of some common indigenous traditional drugs - Punarnava, Vashaka, Anantamul, Arjuna, Chirata, Picrorhiga, Kalomegh, Amla, Asoka, Bahera, Haritaki, Tulsi, Neem, Betel nut, Joan, Karela, Shajna, Carrot, Bael, Garlic, Jam, and Madar.

Section - B

  1. Introduction to the general structure of the morphological parts of plants.
  2. Structure of plants cell, form and function.
  3. Crude drugs: A general view of their origin, distribution, cultivation, collection, drying and storage, commerce and quality control; classification of drugs; preparation of drugs; evaluation of crude drugs; drug adulteration..
  Recommended references:
  1. Evans, W.C. 1989. Trease & Evans' Textbook of Pharmacognosy. 13th edition. University Press, Cambridge.
  2. Ali, M. 1994. Textbook of Pharmacognosy. Satish Kumar Jain for CBS.
  3. Tyler, V.E. and Brady, L.R. 1988. Pharmacognosy. 9th edition. Philadelphia.
Pharm-1102
Pharmacognosy- I Sessional and field work
1  Credit
  1. Collection and identification of mucor, rhizopus, aspergillus, penicillium, yeast and ergot.
  2. Collection and identification of plant parts rich in starch and their derivatives, calcium carbonate and silica.
  3. Study of cell morphology; Parenchyma, cholenchyma, Schlerenchyma, Prosenchyma, Xylem fibers/vessels, Tracheids and stomata.
  4. Collection and identification of some important medicinal plants and extraction of their medicinal components.
  5. Study of some groups of unorganized white and off-white powdered and whole drugs.
  6. Study of some poisonous plants of Bangladesh.
Pharm-1103
Inorganic Pharmacy-I
2  Credit

Section- A

  1. Structure of atoms: An elementary treatment of theories of atomic structure, fundamental particles, simple treatment of quantum mechanics, wave of light, Plank’s Quantum Theory, Pauli’s Exclusion Principle, origin of spectral lines.
  2. Classification of elements: Electronic structure of atoms and the modern periodic table and periodic law, variation of properties within periods and groups, usefulness and limitations of periodic table, pharmaceutically important elements.

Section- B

  1. Chemical bonds: Electronic concept of valency, different types of chemical bonds - ionic, covalent, co-ordinate covalent, metallic, dipole, and hydrogen bonds, theories of covalent bonding and hybridization.
  2. Co-ordination compounds: Definition, Werner’s theory, electronic interpretation, nomenclature of complexes, chelate complexes, Inner complexes, p-complexes, Valence bond theory regarding structure of complex compounds, pharmaceutical importance.
  Recommended references:
  1. Chang, R. 1994. Essential Chemistry. 5th edition. McGraw-Hill Inc., New York.
  2. Haider, S.Z. 1994. Modern Inorganic Chemistry. Friends International, Dhaka.
  3. Haider, S.Z. 1994. Advanced Inorganic Chemistry. Students Publications, Dhaka.
  4. Lee, J.D.1996. Concise Inorganic Chemistry, 15th Blackwell Science Ltd., Oxford.
  5. Ali, M. 1997. Pharmaceutical Inorganic Chemistry. CBS Publishers, New Delhi, India.
Pharm-1104
Inorganic Pharmacy-I Sessional
1  Credit
  1. Qualitative analysis of radicals in inorganic samples.
  2. Identification of inorganic drugs in their formulations: Ca++, Fe++, Al+++, Mg++, K+, Na+.
  3. Conversion of different water insoluble or sparingly soluble drugs into water soluble forms: Na/K-salicylate from salicylic acid; Na/K-benzoate from benzoic acid.; Na/K-citrate from citric acid.
Pharm-1105
Organic Pharmacy-I
2  Credit

Section- A

  1. Introduction: Melting point, boiling point, solubility, acids, bases, polarity of bonds and molecules, intermolecular forces, and isomerism in organic compounds.
  2. Alkanes: Occurrence, structure, nomenclature, synthesis, physical and chemical properties.
  3. Alkenes and alkynes: Occurrence, structure, nomenclature, synthesis, physical and chemical properties including electrophilic addition and free radical reaction, polymerization.
  4. Alcohols, ethers, epoxides and diols: Occurrence, structure, nomenclature, synthesis, physical and chemical properties and uses.

Section- B

  1. Dienes: Structure and properties of 1,3-butadiene, addition reaction, polymerization, Diels Alder reaction.
  2. Aldehydes and ketones: Structures, nomenclature, synthesis, nucleophilic addition reaction, addition elimination reaction, oxidation-reduction of carbonyl compounds, haloform reaction, enolization, halocarbonyl compounds, aldol condensation, benzoin condensation.
  3. Carboxylic acids and their derivatives: Structures, nomenclature, synthesis, properties, reactions, dicarboxylic acids, esters, name and use of carboxylic acid containing drugs.
  Recommended references:
  1. Morrison, R.T. and Boyd, R.N. 1995. Organic Chemistry. 6th Prentice-Hall of India Private Ltd., New Delhi.
  2. Finar, I.L. 1994. Organic Chemistry (Vol. I and II). 6th Longman Group Ltd., England.
  3. Bahl, A. and Bahl, B.S. 1998. A Textbook of Organic Chemistry. 15th Edition. S. Chand and Co. Ltd., New Delhi.
  4. Ali, M. 1995. Textbook of Pharmaceutical Organic Chemistry. 1st Edition. CBS Publishers and Distributors, New Delhi.
Pharm-1107
Physical Pharmacy – I
2  Credit

Section- A

  1. Properties of gases: Gas laws, ideal gas equation, Dalton’s law of partial pressure, diffusion of gases, kinetic theory of gases, mean free path, deviation from ideal gas behavior, van der Waals’ equation, critical constants, liquefaction of gases, Joule-Thompson effect, determination of molecular weight, law of corresponding state, heat capacity.
  2. Chemical equilibrium: Law of mass action, determination of equilibrium constant, heterogeneous and homogeneous equilibrium, the Le Chatelier principle, Van’t Hoff equation.
 

Section- B

  1. Ionic equilibrium: Proton theory of acids and bases, ionization of water, pH, determination of pH of acids and bases, pharmaceutical importance.
  2. Acidimetry and alkalimetry: Fundamentals of acids and bases, titration curves of acids and bases, acid-base indicators and its importance in pharmacy.
  3. Buffer: Definition, buffer capacity, preparation of buffer solution, buffer and isotonic system, methods for adjustment of tonicity of solution, Ostwald dilution law, importance of buffers in pharmaceutical manufacturing, and in biological systems.
Recommended references:
  1. Martin, A. 1996. Physical Pharmacy. 4th B.I. Waverly (Pvt.) Ltd., New Delhi.
  2. Haque, M.M. and Nawab, M.A. 1994. Principles of Physical Chemistry. 3rd Students Publications, Dhaka.
  3. Glasstone, S. 1990. Textbook of Physical Chemistry. 2nd S.G. Wasam for Macmillan India Ltd.
  4. Glasstone, S. & Lewis, D. 1960. Elements of Physical Chemistry. 2nd Edition. McMillan Comp. of India Ltd.
  5. Chang, R. 1994. Chemistry. 5th edition. Mcgraw-Hill Inc., New York.
  6. Bahl, B.S. and Tuli, G.D. 1997. Essentials of Physical Chemistry. 24th edition. S. Chand and Co Ltd., New Delhi.
Pharm-1108
Physical Pharmacy- I Sessional
1  Credit
  1. Determination of M.W. of substances like CHCl3, CCl4 by Victor Meyer’s method.
  2. Determination of heat of neutralization of HCl with NaOH.
  3. Standardization of acids and bases.
  4. Determination of pKa and pKb values.
  5. Preparation of solution of different pH and buffer capacity.
  6. Determination of titration curves.
Pharmaceutical Microbiology- I
3  Credit

Section- A

  1. Introduction: Historical development, scope of microbiology with special reference to pharmaceutical sciences, microscopy.
  2. Characteristics of bacteria: General morphology, size, shape, movement and composition of cell wall, bacterial spores, capsules, flagella, and inclusions and bacterial movements.
  3. Principles of sterilization: Introduction to different methods of sterilization.
 

Section- B

  1. Physiology of bacteria: Growth, growth curve, and growth characteristics, factors affecting growth of bacteria- nutritional requirements, preparation of culture media for aerobic and anaerobic organisms, methods of isolation of pure culture, principal methods of isolation, preservation of cultures by different methods, methods of bacterial counts.
  2. Microbial spoilage and preservation of Pharmaceutical Products
Recommended references:
  1. Pelczar, M.J., Chan E.C.S & Krieg N.R. 1997. Microbiology. 15th Edition, Tata McGraw-Hill Publishing Company Ltd., New Delhi.
  2. Stanier, R.Y. Ingraham, J.L. Wheelis, M.L. & and Painter, P.R. 1993. General Microbiology. 5th Edition. The Macmillan Press Ltd., London.
  3. Choudhury, M.R. 1999. Modern Medical Microbiology. 5th Ganim Printing & Packages, Dhaka.
  4. Levinson, W. & Jawetz, E. 1989. Medical Microbiology & Immunology. 6th McGraw Hill.
  5. Hugo, W.B and Russell, A.D. 1983. Pharmaceutical Microbiology. 3rd Blackwell Scientific Publications, Oxford.
HSS 1151
English
2  Credit
Section- A
  1. Nouns: Countable and uncountable Nouns, Noun Phrases
  2. Pronoun and Pronominal Adjectives: Demonstrative Adjective, Possessive Adjective, Distributive Adjective, Quantitative Adjectives, Interrogatives.
  3. Finites and Non Finites: General uses of Modal Auxiliaries.
  4. Verb Modifiers: Modifier of Time, Modifier of Degree, Modifier of Frequency, Sentence Modifier.
  5. Common sentence pattern.
  6. The tense: Special uses of simple present, present continuous, past continuous, and future continuous tenses.
  7. Conditional sentence types.
  8. Phrasal verbs.
  9. Affixes
Section- B
  1. Reading comprehension to focus on theme/content and grammatical items.
  2. Drafting of Essays.
  3. Paragraph writing.
  4. Dialogue writing.
  5. Letter writing: Letters of Application, Letters of Newspapers, Request letters.
  6. Social, emotional, and moral altitudes.
Recommended references:
  1. Thomson, A.J. and Martinet, A.V. 1994. A Practical English Grammar (with exercise books). 4th Oxford University Press.
  2. A.S. 1975. A guide to patterns and Usage in English. 2nd Edition. Oxford University Press.
  3. Rogers, B. 1996. Petterson’s TOEFL CBT Success, 2nd Thomson Learning, USA.
  4. Sharpe, P.J. 1997. Barron’s How to prepare for the TOEFL, 10th Barron’s Educational Series Inc.
  5. Cambridge IELTS, 2000. Cambridge University
Pharm -1260
Oral Examination-I
1  Credit
An oral examination on the courses of the first year (TERM-I & TERM-II) will be taken after the final examination of theory courses.
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